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I don't know about reverse. But as I remeber according to Dr.Rhonda Patric in one of Joe Rogan show, cold shower can boost protection of myelin.

Senolytics might help reducing aged cells to get benefit. Not directly contribute to brain health I think.

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I like Rhonda Patrick, but a lot of her recommendations seem to be speculation on what should work, given what she understands about a subject and relating it to a new study. Not that it's not valuable, but it's the sort of thing Reddit would class as "science" rather than realising it is a hypothesis that needs testing.

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