1. Around 1971: a Wang desktop computer. Imagine: a computer that fit on a desk!
2. Visicalc (spreadsheet). Wow! I remember thinking finally, a breakthrough for non-programmers.
3. Relational databases.
4. UUCP - a way to talk to remote computers.
5. HTML/HTTP - we knew from the start that this was big
And then there were many that were hyped but which I rejected as hype. Even when I was wrong, I still felt that there was something intrinsically wrong about this category of things.
These things either vanished, limped along (and still do), or which I rejected out of hand, but actually succeeded. Like Virtual Reality (back in about 1984), Fuzzy Logic, Proving programs correct, and, of course Bitcoin.
The latest in this category are NFTs which my intuition tells me is rubbish on so many levels. However, I think they will have some success, although I will never have anything to do with them (or Bitcoin for that matter).