Not really - you need thousands of pounds of ordinance to sink a destroyer and no small UAV is carrying that.
There's a youtuber that has a multi-hour autonomous drone, but it's solar powered and this was at night.
https://dronelife.com/2021/03/18/skyfront-gas-electric-hybri...
That could almost had done what’s reported from land, and easily from a small boat 50 miles away from the ships (which is well over the horizon).