The Future of Perl apparently resides on a JavaScript only site. What a weird world.
But yeah, in a perfect world where we had infinite time to develop it, we'd have the backend serve up a non-javascript static version of the content in response to direct links - if nothing else because it makes things a lot nicer for search engines - and then the javascript would load in and take over if enabled to allow you to keep moving through the site like usual.
FastCGI and mod_perl would have been a better choice.