There are financial primitives that cannot exist in traditional finance that I'd call pretty novel. For example flash loans allow uncollateralized loans for millions of dollars[0]. Or take KeeperDAO[1] or Dai[2] or any of the other meta protocols generating returns by providing utility. Also the sheer fact that this is all decentralized/identity-less is already a novel aspect.
[0] https://aave.com/flash-loans/
[1] https://medium.com/keeperdao/a-keepers-guide-to-arbitrage-mi...