My opinion is that art is not concerned at all with how it's received, only with how it's produced. If you are doing something because you think it will be popular then you are in business, not art.
Of course, people do have reactions to art. But that doesn't change the artistic value of the original piece. If they did, then the artistic value of something would change over time, which seems counter-intuitiive to me.
The interplay between the artist and the consumer of their art is a separate piece of art in itself, which may or may not have been "designed" by the artist.