Yes. I do not get 803 calls at all anymore. Am on iOS 14.4.2. I also use T-Mobile Scam Shield so I can see all the calls that have come in from the carrier’s perspective, so before iOS blocks them.

It’s interesting, of the last 24 calls from the 803 area code (most recent was yesterday) only 9 were identified as spam by T-Mobile and blocked by them. The others were blocked by the WideProtect app. Certain all of them were spam.

(I lived in SC 10+ years ago. The only people I met there are in my contacts and excluded from the blocklist.)