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C-b is what tmux uses because it was developed in screen and and C-a was taken. I always change my tmux config to C-a leader and C-a-a for literal C-a

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C-a is "go to beginning of line" in emacs-bindings for bash, which I use quite often...

There's no way to please everyone :-)

Hence the C-a-a for a literal C-a. It's not the same but hitting control a a isn't much worse than just control a.

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