Do you literally mean all your descendents? E.g. in 200 years there will be 100ish people still substantially benefitting from your wealth? That's how your post reads and is probably how most people would interpret it but I suspect it may not be what you meant.
Or do you just mean your wealth just benefits your immediate descendants? (What you've written would be a very odd way to say that because most people would describe those people as "my children".) Obviously there would still be an indirect effect all the way down e.g. your grandchildren would probably get a better education which would let them earn more for themselves, etc., but that would fade out eventually through the generations.