Why Covid-19 patients become critically ill | Hacker News Reader

Why Covid-19 patients become critically ill

amsterdamumc.org

45 pointssuperjan13 comments

It is kinda funny how human society mirrors the human body. In the small have the innate immune system that buys time for the adaptive immune system. Then in the large we've got a bunch of desperate temporary measures to try and slow disease down to buy time to gather data and logistics for a scientific response. Must be a very stable pattern for dealing with disease.

The coronavirus might be about to win some sort of record for going from novel to what I assume is about to be very, very well understood. Most of the studies that kicked off in early 2020 should be out by now and leaking into medical practice.

Now this is scary and unheard of ???.

Afaik the immune system does occasionally go haywire i.e it attacks "self" (Type I diabetes) because the mechanism that zaps "self" T/B cells goes wrong.

Malformed antibodies seems like something novel in a disease and fundamental new attack vector in a virus ???.

what if it is something related to how Coeliac gets affected. perhaps those people have a particular reactivity towards that virus protein.

Presence of it cause the triggered effect but in the absence it doesnt

I would appreciate more information on how the various kinds of vaccines impact chances of getting a cytokine storm.

I think it might still be too soon to tell with vaccines. A lot of information from last year regarding effective treatment by using monoclonal antibodies to help combat patients actively experiencing a cytokine storm though.

This was discussed in the comments on a preprint of a related paper by the same authors. http://disq.us/p/2akcsb2

It's sad that medical advice offers little to people, effectively waiting until people are suffocating to rush them to the hospital.

There's something seriously broken about how people are being treated.

Since this serious complication first surfaced a little over a year ago, various mitigations have been developed, with the result that people with this complication are more likely to survive than before. Now, the mechanism responsible for it has been discovered, an an apparently-effective solution found among existing drugs - and the search for more continues.

Just what is "seriously broken" about this picture, other than that it does not conform to your fantasy about how things should be? Overfilling the hospitals with everyone who might develop this complication would be counter-productive.

We are seriously overlooking the general prophylactic and tonic benefits that would lead to fewer people landing in hospital ICUs and requiring serious medical intervention that itself often has harmful and long-lasting side effects. The healing properties of an anti-inflammatory diet rich in turmeric and wild-caught salmon are well-understood. Honey has clear anti-bacterial properties. Air rich in ions leads to improvements in general well-being. If we listened to what Mother Nature was telling us (especially about the healing wisdom of wildcrafted dark chocolate), we likely wouldn't feel a need to rush to all these unpronounceable drugs of dubious benefit.

As far as panaceas go I'd take tasty food over bleach enemas at least, I'll give you that

There is no healing wisdom in a bleach enema.

I always wonder, how people like you end up on HN. Its like meeting a mormon in a pub.

Please don't break the site guidelines like this, regardless of how wrong someone is or you feel they are. It only makes the community worse.

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