may i ask what field of knowledge the manipulated paper was from? Your page lists CS/NLP, so that field may also be linguistics or neurology (linguistics which would be easier to swallow for me) https://scholar.google.com/citations?user=FMScFbwAAAAJ&hl=en

Some wider questions would be: Are there similar problems in Mathematics/physics versus the life sciences/other social sciences? Are there the same kind of problems across different fields of study?

Also i wonder if replication issues would be less severe if there was a requirement to publish the software and raw data that any study is based on as open source / data. It is possible that a change in this direction would make it more difficult to manipulate the results (after all it's the public who paid for the research, in most cases)