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You can connect many NVMEs to a single CPU, but the PCI bandwidth becomes a bottleneck much earlier of course. Just as with SATA. Think of the SATA HBA as an adapter that bridges between PCI and SATA. For NVMe the counterpart is a PCI switch, with PCI on both sides.

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Supermicro sells single-CPU servers with 24 NVMe bays. Not a big problem if your CPU has 128 PCIe lanes.

You could get 12 quite easily even on consumer hardware. AMD Threadripper gives you 64 PCIe 4.0 lanes (so up to 72 with the TRX40 chipset), so you just use three PCIe x16 expansion cards each providing four NVMe 4x slots.

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