From what I gather from the paper, they frame the problem of test generation as a search problem. An evolutionary algorithm randomly mutates a randomly generated test suite. The evolutionary algorithm optimizes for greater branch coverage.
Excerpt from the abstract:
"Our experiments confirm that evolutionary algorithms can outperform random test generation also in the context of Python, and can even alleviate the problem of absent type information to some degree. However, our results demonstrate that dynamic typing nevertheless poses a fundamental issue for test generation, suggesting future work on integrating type inference"