Stripe is ONLY a payment gateway, 'Stripe handling taxes' is a complete myth that is always brought up by uninformed US Stripe customers only to hype Stripe up.

Stripe customers in the EU have to deal with this VAT tax pain already which is why they either don't use Stripe and use Paddle instead.

There is another type of service becoming increasingly prominent, which is a "merchant of record". In effect, the service becomes a reseller for your product or service, and since they are then the vendor for legal purposes, they also become responsible for all the end customer taxation issues. You in turn typically deal with them as a much simpler B2B relationship between just two entities.