Win+PrtScr saves the screenshot as a PNG file in Pictures\Screenshots.

Windows also ships with a tool called Snipping tool[0], but that now says that it will be replaced by Snip & Sketch [1].

If you want to quickly take a cropped screenshot you can use Win+Shift+S. It only saves to the clipboard, but a lot of places, like imgur and Github, supports pasting images so I often find it more convenient than to have a bunch of old files cluttering the system.

[0] https://support.microsoft.com/en-us/windows/use-snipping-too...

[1] https://www.microsoft.com/en-us/p/snip-sketch/9mz95kl8mr0l?a...