I don't understand people who say things like "I will live with the time I'm given". Do you reject modern medicine because that's an unnatural extension of your time? If you had a fatal illness that could be cured would you refuse treatment? Hand soap, fertilizer, and modern nutrition have likely extended your expected lifespan. Do you go without those as well?
I think it can sound romantic to stick with your natural span. Especially if that span extends out for decades yet. I expect it's another matter entirely to be on death's door.
A less selfish way to think about it is to imagine an elderly loved one. If your mother could take rapamaycin and live an additional 40 years in good health, would you prefer she die at 80?
I think death is a very bad thing and having a way to put it off is very good. Fatalistic attitudes confuse the issue.