You might find this of interest too from eleven years ago: https://drhyman.com/blog/2010/12/09/breakthrough-discovery-o... "Let’s look more closely at what this new study in The Journal of the American Medical Association tells us about mitochondrial dysfunction and how this may lead us to new methods of treatment—methods similar to the ones I used to help reverse Jackson’s autism. ... This study forces the question: How do children acquire energy deficits that affect their whole system, not just the brain? The causes of mitochondrial dysfunction are well known, specifically as it relates to metabolism and the brain, and I have documented them in my books UtraMetabolism and The UltraMind Solution. They include environmental toxins(iv)—mercury, lead and persistent organic pollutants(v)—latent infections, gluten and allergens (which trigger inflammation) sugar and processed foods,(vi) a nutrient-depleted diet,(vii) and nutritional deficiencies.(viii) These are all potentially treatable and reversible causes of mitochondrial dysfunction that have been clearly documented. I found all these problems in Jackson, and over a period of 2 years we slowly unraveled and treated the underlying causes of his energy loss which included gut inflammation, mercury, and nutrient deficiencies. Over time, the tests for his mitochondrial function and oxidative stress (as well as levels of inflammation and nutrient status) all normalized. When they became normal, so did Jackson. He went from full-blown regressive autism to a normal, bright beautiful 6-year-old boy. This is just one story, but if autism can be reversed in one child, if there is any possibility of effective treatments or a potential cure, it forces us to ask critical questions: How did this happen? Can it happen in other children? What were the biological patterns found and how were they treated?"
And if it applies to young brains, why would it not apply to older brains?