For instance, I know some folks who'd like to build a new kind of nuclear reactor that uses molten Thorium salt as a fuel. The kind of system could produce all the energy you use in your life with a ball of Thorium that you could hold between two fingers.
It would probably cost these guys $500M just to fill out the paperwork to build a test reactor... Even Silicon Valley investors don't want to spend that much cash. if you think the RIAA is bad just try the NRC.