"Although this is not the case of the authorized COVID-19 mRNA vaccines, future formulations containing adjuvant like TLR agonists [13] may exacerbate pre-existing autoimmune or autoinflammatory disorders and should therefore be discouraged in this cohort of patients."
I guess this mostly relates to the "packaging" of the mRNA vaccines relating to the entry in the cells.
I think there was another one talking about 50% of severe covid patients developing autoimmune antibodies, but with no idea if they will progress to a condition.
I was hoping to see some longterm studies from prior mRNA research. But it's my understanding that the longer research wasn't about inducing immune response but for trying to modify DNA to correct genetic conditions (which failed, but now crispr...).
Maayan, H., Kirgner, I., Gutwein, O., Herzog-Tzarfati, K., Rahimi-Levene, N., Koren-Michowitz, M., & Blickstein, D. (n.d.). Acquired Thrombotic Thrombocytopenic Purpura: A rare disease associated Acquired with BNT162b2 vaccine. Journal of Thrombosis and Haemostasis, n/a(n/a). https://doi.org/10.1111/jth.15420
Yocum, A., & Simon, E. L. (2021). Thrombotic Thrombocytopenic Purpura after Ad26.COV2-S Vaccination. The American Journal of Emergency Medicine. https://doi.org/10.1016/j.ajem.2021.05.001