Booksmart was the first thing I thought of too when he said, “since 2012, the only successful comedies have been animations aimed at young children.” (edit: I mean to say, you can still see movies with originality even if they're not "successful" i.e. blockbusters)
In 2018 when I originally got AMC A-list subscription, I tried going to 3 movie a week at first, so I went to a lot more movies I was unsure about but they were very original and memorable, but they weren’t super popular (at least I was the only person I personally knew who had seen it).
Sorry to Bother You ($18 million)
Blackkklansman ($93 million)
Eighth Grade ($14 million)
Crazy Rich Asians ($238 million)