Let's think about the internet. Let's think about how it enables us to achieve instant communication all around the globe and freely share and distribute knowledge too great to hold in one's brain. I'd say the modern men are more than capable of overcoming biological barriers once thought to be fundamentally impossible to achieve.

It might be a fairly rough road to get there, but I'm certain our understanding of how our brains perceive pain and pleasure will be dramatically different in a 100 years, and it'll be for the better.