Yeah, but even Jeet Kune Do has already died out almost entirely in favor of a combination of (Muay Thai, BJJ, and either Greco-Roman wrestling or Judo) aka MMA. Maybe throw in some Krav Maga for defense against common street attacks and you're set.
Realistically, hybrid martial arts have been around for a long time. When I was a kid (long before the MMA hype train), I did Karate, but it also involved learning ~30 judo throws, a lot of jujitsu, as well as a wide variety of weapons (bo, nunchucku, kama, eiku, sai, tonfa) as all of the instructors also were black belts in some Okinawan weapons art. It was a lot of fun and better than any martial arts training I had previously (made the years I spent on Taekwondo feel embarrassing), but still nearly useless against a mediocre Muay Thai and BJJ fighter.