This is just one example of the "analogue hole" [1] problem shared by all anti-cheat/DRM systems. At least in theory, there is no technology that can prevent exploits like this short of dystopian levels of surveillance and locking down computing devices even further. By that I mean encrypted communication on all computer buses (including USB, HDMI), and only allowing access to those busses via physically hardened "secure" enclaves, up to (in the end game) big-brother-like surveillance (think electronic proctoring solutions). I think that this is exactly the problem with such DRM schemes---the ensuing cat-and-mouse game will inevitably lead to trampling the user's freedoms, because locking down computing devices and environments to ridiculous levels is the only way in which DRM can be made to work.

Of course, for now, cheats like the one featured in the article should be fairly easy to detect (at least from what I've seen in the linked video). The motion of the bot is extremely jerky; a simple rule-based system, or, if you want to be fancy, a neural network based anomaly detection system should be able to detect this.

On the side of the cheat authors, this could be easily circumvented if they include a "calibration phase", where user input trains a simple neural network to stochastically emulate the dynamics of the user's sensor-action loop. The cheat could then act slightly faster than the user, giving them an edge while still using their unique dynamics profile.

I wonder where this will lead eventually, and I genuinely feel sorry for all the people who pour their heart and soul into competitive gaming; I don't think that this kind of cheating is something that can and should (see above) be prevented in the long-run. The best possible outcome I can imagine is that online gaming becomes more cooperative or once more converges back to small groups of people who know and trust each other.

[1] https://en.wikipedia.org/wiki/Analog_hole

Edit: Spelling, grammar, and clarity