Ivermectin has been know about since April 2020 when the Caly paper showed in-vitro that at high doses, ivermectin had anti-viral properties (sars-cov-2 sends proteins into the cell nucleus to turn off your immune response (interferon)). However, western scientists thought this anti-viral effect was implausible (https://www.microbe.tv/twiv/twiv-599/) - they were mostly correct as the effect is most likely immunomodulatory (Melo et al). Thus, NO clinicial trials of Ivermectin have been completed in the West (apart from a tiny 20 person trial in Barcelona). In contrast, the developing world has completed 30 randomized controlled trials (RCTs) and 60 trials in total - https://ivmmeta.com/. Ivermectin is safe (a WHO approved essential medicine), so we only care about efficacy. It is safer than paracetamol and has been taken billions of times. No trial completed to date has shown that it does not have a positive effect. Most trials have shown statistically significance on the most important clinical outcomes - hospitalization and death.

Ivermectin works best when given early. It is transforming treatment and having incredible success in places like Uttar Pradesh (200+ million inhabitants, with only 38 new cases and 1 death yesterday - https://www.covid19india.org/).

So, Ivermectin is an enormous threat to the Pharma industry. Merck (who discovered Ivermectin and help cure river blindness by donating it) are down-talking it, so they can bring Molpuvanir to market (they got a couple of billion from the US govt for this recently). Vaccine manufacturers run negative ads on google against Ivermectin (https://www.biznews.com/thought-leaders/2021/05/12/mailbox-i...). AND the person who discovered the fake data in the trial linked was supposedly a masters student, but he runs an investigative service and the level of sophistication in finding the data showed higher involvement - https://trialsitenews.com/ivermectin-study-appears-fraudulen....

This is like the tobacco industry funding scientific trials. We already had a discredited Jama paper (https://jamaletter.com/) on Ivermectin/Covid. So they can do it, but I really hope the truth on Ivermectin - that it is an effective treatment for Covid - comes out. Otherwise, I will despair for society and advocate revolutionary change. However, the 2 big western trials being funded are being funded by the vaccine manufacturers (indirectly, of course), via Macmaster Univ (Gates-funded) and Oxford (Gates funded). RCTs can be designed to not succeed (it can't fail with Ivermectin, only not shown huge effect), and these are designed so - Bill

* Caly et al - https://www.sciencedirect.com/science/article/pii/S016635422...

* Melo et al - https://research.pasteur.fr/fr/publication/attenuation-of-cl...

https://sebastianrushworth.com/2021/05/09/update-on-ivermect...