There was a fascinating example of strong dependence on the initial problem specification in an early hardware-evolution experiment in the 90s. The evolved chip for an audio-processing task was massively smaller than the best human-designed chip, which turned out to be because rather than sticking to digital-logic design, the evolutionary process had taken advantage of electromagnetic interference between circuit components as a core aspect of the design (this was possible because the evolution was done on FPGAs, not in a simulator). But as a result, it only worked at the temperature it was evolved at!

One of the papers: http://www.informatics.sussex.ac.uk/users/adrianth/ices96/pa...