The resistance tends to last only a few generations before the pest population evolves past it.

In areas where BT-Maize gets planted, Corn Ear Worm has been observed to evolve resistances in as few as 5 or 6 generations. You might think you've deployed a pest-free plant, but in reality all you've done is deploy an evolutionary pressure on the target population, and nature has had like 800-million years' practise out-evolving bad shit happening.

Viewed in a systems light, the whole notion is little more than a grift; at best a temporary solution that takes longer to develop than ecosystems take to out-evolve.

"By 2018, farmers were spending an average of $23.58 per hectare on insecticide — 37% more than the pre-Bt levels." https://www.thehindu.com/opinion/op-ed/the-twisted-trajector... Unfortunately the field isn't a lab, and making it look like a lab is very resource-intensive and environmentally damaging. "The cost of ignoring ‘desi’ varieties for decades has been high for India."

But how does that allow our company to sell more pesticides?