I had a bad concussion when I was 12 and ever since (I’m 33 now) I’ve had issues. Fatigue is the big one, but I also lost 2 inches of height, my feet shrunk two sizes, and my hands are as small as my mom’s. I’m male. There are other possible symptoms too, like cold hands and feet and too much heat/sunlight making me worthless for the next day or so. As I’m sure you know it can be hard to know which symptoms to group together. Are my cluster headaches related? Who knows.
The only actual treatable aspect of this that they’ve found is my testosterone being too low. Supplementing that helps significantly, but it’s not enough. I personally think my growth hormone levels might be off, but my GP doesn’t know how to run the test for that and endocrinologists are the worst.
I’ve been to Mayo quite a few times. The last time I was there the best guess they had for the testosterone problem was that my body thought it was dying, so it was diverting resources.
I know that we don’t know everything and sometimes you’re out of luck, but it’s still frustrating nonetheless. It’s even worse when they can’t find anything physiological to test for. Before I asked to have my testosterone levels checked they just threw me on antidepressants and called it good. The only thing I was depressed about was being so damned tired all the time.