As you mentioned, it's also not intuitive. It's by now well-digested, but it's a fairly surprising theorem, even to Brouwer.
Finally, it's not constructive. Generally you can't figure out which point is fixed. If I recall correctly, frustration with this fact fueled Brouwer's interest in intuitionism, which gives us a type of logic where some propositions are neither true nor false but essentially undecidable.
I'm not sure what you mean by a "particle" in your sentence. If you mean to go down to the quantum scale, then I'm sure all sorts of things go wrong in trying to apply the theorem. For one, even talking about the position of a particle at all is very different from talking about a point in Euclidean space.
If you don't mean to go down to the quantum scale, then lots of maps have fixed points. Rotations an reflections are two large classes of examples.