You would think that it would be profitable enough for them to become their own bank and processor if no one else would. This right here tells me they knew they couldn't. Why? Who is telling them no? How can we live in a place where LEGAL businesses are purposefully excluded from the market?
I think they should start taking Bitcoin or Monero. Fuck MasterCard and whoever dictates what they do. If you are going to be forced into bankruptcy, at least do it in style.