The study of obesity is the study of mysteries
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Can we link childhood obesity to areas with particularly high rates of some kind of industrial contamination? (Poverty as a confounding effect may make this hard)
If the watershed is part of the mechanism, can we confirm lower obesity rates in areas without much industrial pollution that have similar diet & exercise to obese areas? (Independent of the already-mentioned altitude effects)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991921/
Healthy diets strongly correlate with both sufficient fiber and healthy BMIs. The point is that 95% of people don't have healthy diets. As long as diets remain so poor -- the phrase "standard American diet" purposely forms the acronym SAD -- there is no obesity mystery.