Apple Notes takes the crown for being the most unobstructive when it comes to taking notes.
1. Drag and Drop images, screenshots, annotate them in place. I cannot live without this anymore. Forcing me to first upload an image somewhere, and then use ()[] syntax to correctly load the file in MarkDown is the opposite of what I want my Notes application to be.
2. Sync - I write my notes on my Mac while working. I needed to look something up while I am waiting in queue somewhere? iPhone provides an excellent interface with usable Search while on the Go. Had a thought while I am traveling, want to put it down? Notes on iPhone. This thing is super convenient.
3. Shared Notes. My wife and I share a few notes with purposes - "Things to Know" - for the important tidbits that we end up sharing via Messages/email. Now they are in one place and recorded forever. "To buy" is our commonly used shopping list. "Household todo" - is our shared todo list for stuff around the house.
Now, the con is that deep lock-in to the Apple ecosystem. I am still waiting for an alternative that gives me the ability and ease to do #1 and #2 above. So far, none met my needs.
My eager bet is on https://www.serenity.re/en/notes The dev has image drag and drop support on the roadmap. If it comes out, I will give it a serious shot.