My last doctor (a very good, well-known Rheumatologist in my area) spent a long time working with me. After months of trying everything he knew, he put it to me like this:
* You have Chronic Fatigue Syndrome. Name sucks, but that's what it's called right now.
* What you have is real, it's not "in your head".
* A typical outcome is that you will start to feel better when you turn 50 or 60. In other words, my best outcome is to hang on for another ten to twenty years and hope that I feel better then.
I've been dealing with this since college, but this is the year that I finally had to admit I was failing, and had to quit my job.