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Comment by dogma1138 | Hacker News Reader

It would be interesting to see the duration of the immunity or resistance across multiple vaccine variants. The latest data from the UK indicates that the AZ vaccine suffers less degradation over time than Pfizer, at least when it comes to the Delta variant which is now the prevalent one in the UK.

Israel has now giving boosters to 30 year olds and older in order to boost the immunity to infection and resistance to severe illness.

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My understanding is that it may be due to the difference of time during the two shots. It's possible that 2 weeks between the two shots of Pfizer is too short. We're learning.

In the UK Pfizer and AZ both are on 8 weeks protocols and the UK has seen a sharper drop in Pfizer efficacy compared to AZ.

I got Pfizer in the UK, I also suspect to have had it in March (3 days of some coughing and loss of smell), I’m under 40 so no AZ for me.

In part due to immunity duration concerns and, honestly, in part due to supply issues - Canada ended up going way wide on vaccines - most people ended up with twelve weeks between vaccinations.

Canada also made the bold move of mixing different vaccines, even though there were zero clinical trials of multi-vendor vaccines.

Pfizer is 3 weeks, Moderna is 4

Moderna apparently has a 33% higher volume dosage?

It's 3x larger, at least by the amount of mRNA.

But the lower efficacy drop of Pfizer is still higher than the less degraded AZ efficacy...

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