Other than the obvious economic impacts of the pandemic on small businesses, the de-stressing activities I personally enjoy - lifting weight, martial arts, going to the cinema - have been unavailable for most of the pandemic. I think that this has led to a less well-defined stopping point at the end of each day both physically and mentally.
The knock on effect of this has been more chronic stress. Before I had a really strong demarcation between the working week and my leisure time: up until things opened up again recently (Scotland), I haven't.