This where you end up with DOS, Windows 3.1 and even Windows NT computers controlling machines that make millions of dollars worth of product, 24 hours a day.
We've spent hours scouring eBay or industrial auction sites finding parts of computers to keep 'just in case'. None of this software virtualizes easily or can even be moved to a machine of similar vintage without relicensing. Some of it is hardware dongles, some of it software keys.
It seems like you could create quite a business being able to crack this software. Companies would pay tens of thousands to get these machines running. Often times the 'new' version of the hardware and software is $100,000 US.
In a few years, internet-based licensing will be the thing to crack.