It's just a matter of time (I don't say that lightly, I have made my donations to support relief efforts from recent policy decisions).
Personally, I don't think "quality of life" is the word that should be used to distinctualize rural and urban living. I've lived in both and had a quality life in both, each came with their tradeoffs and sharp costs I had to manage.
It's also a solid investment to purchase real estate in a place you know quality of life will improve.
Sort by counties in descending order closest to ~50% blue for targeting relocation suggestions, turning counties that flip solid blue. Best bang for your buck imho. Probably cheaper housing too, close enough to urban cores for hybrid remote, far enough out to be affordable. A couple days worth of CRUD/GIS/data science work if I had to hazard a guess.