You can have my mouse and keyboard when you pry them from my cold, dead hands! (Or alternatively: When you invent input devices that are genuinely better for the purposes of inputting huge amounts of text and indicating intent on a large display mounted in an ergonomically suitable position)

I think that our current idea of what a PC is in in its twilight, however. A co-worker bought a brand new Macbook which proceeded to self-destruct (it quite literally melted) 2 weeks after they purchased it. The Apple store turned around a new one in minutes, obviously, but I couldn't help think - in a year or two from now, all his apps would be storing their data through Apple's cloud. The hardware would be completely fungible in that case, and failure would be an almost non-event compared to how much hassle it is currently.