YMMV but I’ve noticed that cloudflared has stability issues over time whereas dnscrypt has been rock solid for me (I run both on different systems). Probably going switch everything to dnscrypt esp since it supports odoh now.
OTOH, I'm beginning to migrate to pfsense and pfblockerng at home. So, it is possible that I may retire my pi-hole at some point. Currently I'm running both as I transition and test.