I've used AWS, Digital Ocean, and Vultr each for multiple years. I've had one major outage on AWS and another on Vultr. I'm currently feeling out Oracle cloud.

I wouldn't hesitate to run significant sites on any of these providers. Problems and outages happen, I don't think anyone is really providing five 9s whatever they say.

One can definitely run a top-tier service on nine fives metal. It's basics of SRE.