Takes me a little longer on Zoloft. My psychiatrist and I agreed this is more of a good thing than a bad thing. The crippling anxiety I had without it was much worse for my libido.
That being said, I wish we understood these drugs better, because I know the side effects and efficacy vary in the extreme. I know for some people it's like trying to put out a fire with gasoline.
Continued anecdata: when I forget to get my refill, the withdrawal is terrible. Dizziness, malaise, and "brain zaps". One of these days I'm going to have to wean off of it carefully before I try psychedelics.