So you go to a malicious website and it's able to move your mouse around or lock it in place. That would not be a good situation to be in, especially for the segment of the population that doesn't understand keyboard shortcuts (which would, presumably, allow escape from this). Even if it's not used maliciously, it seems very plausible that it would be used to make advertisements harder to avoid (on websites like Hulu that run ads during a video, preventing most users from being able to go elsewhere during them could be a tempting idea).
I get why something with this effect is necessary if we are to have FPS games running in the browser, I just don't think that it's a good idea to allow websites to do so without explicit user permission. Admittedly, there are few things I hate as much as programs moving my mouse around, so I'm a bit biased.