I really hope Skype lets GroupMe continue to operate on it's own, and doesn't ruin it. It's an awesome service, and lets me keep in touch with my tech-adverse friends from back home. Some people use AIM, some use Facebook, some use email, some use MSN, some use BBM -- but everyone has texting.
The beauty is the simplicity. On vacation with some friends? Spin up a new groupme for the week. I can't see it remaining this easy if skype starts taking advantage of "integration points".