I'm something of an elixir zealot, but I have to say that Clojure has the most pleasurable syntax for this kind of thing out of any programming language.
The reason LFE didn't do it for me was that Elixir is relatively painless syntax-wise, and has really nice high-level libraries like Phoenix and Ecto that simplify a lot of work. If I don't need the BEAM, than I'd rather have a more strictly functional language like Clojure, or something more low-level like Common Lisp. LFE doesn't occupy a niche in my personal ecosystem. That being said, I'd definitely give it another try sometime, and I'd recommend it to anyone else who wants to feel the power of the BEAM.