It absolutely makes a difference, because we need to stop this from happening again. We can't just accept that labs are going to continue to release dangerous viruses and then just deal with the effects every time.
So if it's lab leak, the problem isn't the US or Russia or Butan doing lab work. It's China doing lab work insecurely.
And if it's a food hygiene thing, it's not a world food hygiene thing, it's a Chinese food hygiene thing.
So the action here is to sanction the fuck out of China. And that is true whether it's lab leaked or zoonotic or any other unimaginable source.