Until they start suggesting friends of friend's tweets. Or random trending/suggested tweets. Or you might like your friend's tweets but get fed with all of their garbage "liked" content and can't filter that out.
I definitely filter those out.
About once every 6 months the tweets "liked" by people I follow pop up again, it's usually very noticable as the feeds quality turns down dramatically.
To get rid of those, I do the "..." > "I don't like this tweet" > "show fewer likes from XYZ" on 2 or 3 tweets, and they're all gone for another few months.
It's not ideal, a settings menu where you can disable those permanently would be far better, but it works.
If you’re seeing a lot of friends-of-friends content, you might be scrolling too long or not following enough people you actually want to hear from.