Startup time might be a factor. But the measurements of the same language running on the same provider's infrastructure go from around 10 to 50ms (on one provider) and 10 to 100ms (on the other). Those huge differences don't look like CPU latencies (the machines aren't 5x or 10x faster in different locations) - they are likely network latencies. So programming language is probably a very minor factor here (at least in the non-beta services, which is what was measured here - maybe it was an issue in the older measurements).