There doesn't seem to be much evidence companies with fewer than 25 employees are getting sued unless there's something left unspoken here.
I think it would be more constructive to begin the discussion of what patent reform should resemble so that companies and individuals can show support for it. Some kind of software patent working group that can put forward a vision that everyone can get behind. If enough people and companies come to support a way of thinking then it will slowly affect current behavior and ultimately shape the legal framework of the future.
Even if it was a problem that companies smaller than 25 were being sued for patent infringement, I'm not sure the legal litmus test should be how many employees are at the company.