Covid-19 Vaccine Makers Unsure If Fine-Tuning Shots for Omicron Is Worthwhile

Key quote: "Evidence is building that this phenomenon, also known as immune imprinting, is at work in Covid-19. The implication: Boosting with an Omicron-specific vaccine might only reawaken earlier immune responses, whether they were spurred by vaccination or infection. In other words, an Omicron-specific vaccine may have no advantage over simply boosting with the original vaccines."