Well we can use this to execute a reductio ad absurdam on scientific materialism. Let us assume that the logic of cause and effect is all there is to the universe. Then the big bang must have had a cause, and that cause a cause in turn, and so on. That's obviously absurd, even if we point at time beginning with the big bang. Within any human reasoning, things do not appear ex nihilo.

The alternative is that the thing on which our universe depends (being careful not to say 'caused' here) is beyond our ideas of cause and effect, and certainly passes human understanding.