Alibaba recently announced new CPU they developed based on ARM: https://www.tomshardware.com/news/alibaba-unveils-128-core-s...
Furthermore, what we're talking about here is replacing x86. There is indeed a joint venture with AMD, but at the end of the day x86 is still US intellectual property and thus susceptible to sanctions.
It would be a different matter if they decide to replace x86 wholesale with something else, e.g. ARM or RISC-V. That is certainly more feasible today than a decade ago, with Android being a major platform and no longer being constrained to just Windows. But it's probably still a large amount of effort.